Mycodays

20-22 juin 2022
Amphithéâtre Charles Mérieux
Ecole Nationale Supérieure de Lyon

Programme

Monday 20^th of June

12h30 Welcome Snack

13h30-14h00: Meeting introduction, on behalf of the organizing committee

TB : global disease

14h00-14h30: Lucica Ditiu: Ending TB in the post covid era – can we do it?
14h30-15h00: Jonathan Hoffmann: Implementation of multi-country translational TB research within GABRIEL international network
15h00-15h30: Eamonn Gormley: “Vaccination of badgers with BCG to aid eradication of bovine tuberculosis”

15h30-16h00: coffee break

MTB lipidomics

16h00-16h30: Jérôme Nigou: A Mycobacterium tuberculosis fingerprint in human breath allows tuberculosis diagnosis
16h30-17h00: Emilie Layre: Extracellular vesicles released during Mycobacterium tuberculosis infection: lipid content and role in host-pathogen interactions
17h00-17h30: Short oral communications session

• Tonia Dargham : Selection of new therapeutic targets in relation with Intrabacterial Lipid Inclusions metabolism in Mycobacterium abscessus
• Mélanie Foulon : Acquisition of host derived lipids by intracellular mycobacteria and its impact on pathogenesis

17h30-20h00: Posters and local organic aperitifs 

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Tuesday 21^st of June

New strategies to explore host-pathogen interactions in mycobacterial infections
09h00-09h30: Julien Vaubourgeix : Multiform antimicrobial resistance in mycobacteria
09h30-10h00: Céline Cougoule : Human bronchial organoids unveil druggable pathways against Mycobacterium abscessus infection in cystic fibrosis
10h00-10h30: Short oral communications session

• Lucia Grenga : Direct and quick detection of Mycobacterium in cystic fibrosis pulmonary samples, its taxonomical typing, and functional characterization 
• Arnaud Machelart : Intrinsic antibacterial activity of beta cyclodextrins potentiates their effect as drug nanocarriers against tuberculosis

10h30-11h00: Coffee break and posters

11h00-12h00: Short oral communications session

• Emilie Doz Deblauwe: Les neutrophiles régulateurs s’accumulent chez la souris formant des granulomes encapsulés
• Jahn Nitschke: A 3R infection model to screen, characterize and decipher the mode of action of novel anti-mycobacterial compounds from a large plant extract
• Audrey Bernut: Pharmacological activation of NRF2 has protective effects during Mycobacterium abscessus infection by promoting host defenses and reducing inflammatory damage
• Hamadoun Touré: Mycobacterium abscessus resists the innate cytotoxic response by surviving granzyme-mediated cell lysis of infected phagocytes

TB between bench and clinics
12h00-12h30: Maya Hites: Pragmatic management of TB patients in high income countries

12h30-13h30: Lunch and poster

13h30-14h00: Jacinta Bustamante: Mycobacterial diseases in patients with inborn errors of immunity
14h00-14h30: Virginie Rozot: Multidimensional analysis of immune responses in TB
14h30-15h00: Philippe Leissner: Blood transcriptional biomarkers in tuberculosis. Do they meet the needs?
15h00-15h30: Short oral communications session

• Rim Bayaa : Distinct Cellular Signatures Identified by Spectral Flow Cytometry upon Tuberculosis Diagnosis and at Treatment Completion
• Fadel Sayes : Exploring new recombinant BCG Vaccines and different Vaccination Routes for better Tuberculosis Protection

15h30-16h00: Coffee break

Drug discovery for MTB

16h00-16h30: Ruben Hartkoorn A novel potent class of nature inspired anti-tuberculosis molecules: chemical vs genetic plasticity
16h30-17h00: Kamel Djaout : Boosting pretomanid potency: towards reversion of resistance
17h00-17h30: Pierre Santucci: Intracellular localisation of Mycobacterium tuberculosis affects efficacy of the antibiotic pyrazinamide

18h00: Visit Lyon and «Fête de la musique»

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Wednesday 22^nd of June

Pathogenesis and emergence of mycobacteria

9h00-09h30: Estelle Marion: Reconsidering the role of mycolactone in the pathophysiology of Buruli ulcer.
09h30-10h00: Jona Karam: Unraveling the function of tetraspanin CD81 and its cognate adhesins from Mycobacterium abscessus during host cell invasion
10h00-10h30: Short oral communications session

• Virginia Pichler : Unpacking the molecular determinants of Mycobacterium abscessus infections
• Marion Lagune : Les protéines EsxU et EsxT sécrétées par le système de sécrétion ESX-4 modulent la fitness de Mycobacterium abscessus

10h30-11h00: Coffee break

Lessons from Mtb genomics

11h00-11h30: Christophe Guilhot: Emergence of tuberculosis bacilli: the long road to becoming a pathogen
11h30-12h00: Jan Madacki Exploring horizontal gene transfer in predominantly clonal tuberculosis-causing mycobacteria
12h00-12h30: Short oral communications session

• Charlotte Genestet : Mycobacterium tuberculosis genetic features associated with pulmonary tuberculosis severity
• Christophe Sola : Le chaos croissant de la génomique des populations des bacilles de la tuberculose à l’ère des «big data» : il faut trier le bon grain de l’ivraie

12h30-12h45: Meeting conclusions and farewell

Comités

Appel à communications

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Inscriptions

* à jour de cotisation 2022

Modalités d’annulation
La substitution par une autre personne est admise sans pénalité si la SFM en a été informée par écrit avant le colloque.
Toute annulation doit être effectuée par écrit à comptabilite@sfm-microbiologie.org.
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Informations pratiques

Amphithéâtre Charles Mérieux
Ecole National Supérieure de Lyon

Arrêt :
T1- Debourg
B – Gare d’Oullins

Sponsors

Vous souhaitez nous soutenir et devenir sponsor de cet évènement, merci de contacter la SFM
36 avenue Jean Moulin
75014 Paris
Tél. 09 63 04 70 73
Olivia Vong : o.vong@sfm-microbiologie.org
Gaëlle Hennet : g.hennet@sfm-microbiologie.org