Article coup de coeur Sécurité et Sûreté Biologiques

Laboratory-acquired infections and pathogen escapes worldwide between 2000 and 2021: a scoping review

et al.

Open AccessPublished:December 12, 2023
DOI: https://doi.org/10.1016/S2666-5247(23)00319-1

Summary

Laboratory-acquired infections (LAIs) and accidental pathogen escape from laboratory settings (APELS) are major concerns for the community. A risk-based approach for pathogen research management within a standard biosafety management framework is recommended but is challenging due to reasons such as inconsistency in risk tolerance and perception. Here, we performed a scoping review using publicly available, peer-reviewed journal and media reports of LAIs and instances of APELS between 2000 and 2021. We identified LAIs in 309 individuals in 94 reports for 51 pathogens. Eight fatalities (2·6% of all LAIs) were caused by infection with Neisseria meningitidis (n=3, 37·5%), Yersinia pestis (n=2, 25%), Salmonella enterica serotype Typhimurium (S Typhimurium; n=1, 12·5%), or Ebola virus (n=1, 12·5%) or were due to bovine spongiform encephalopathy (n=1, 12·5%). The top five LAI pathogens were S Typhimurium (n=154, 49·8%), Salmonella enteritidis (n=21, 6·8%), vaccinia virus (n=13, 4·2%), Brucella spp (n=12, 3·9%), and Brucella melitensis (n=11, 3·6%). 16 APELS were reported, including those for Bacillus anthracis, SARS-CoV, and poliovirus (n=3 each, 18·8%); Brucella spp and foot and mouth disease virus (n=2 each, 12·5%); and variola virus, Burkholderia pseudomallei, and influenza virus H5N1 (n=1 each, 6·3%). Continual improvement in LAI and APELS management via their root cause analysis and thorough investigation of such incidents is essential to prevent future occurrences. The results are biased due to the reliance on publicly available information, which emphasises the need for formalised global LAIs and APELS reporting to better understand the frequency of and circumstances surrounding these incidents.
Partager cet Article
Avez-vous aimé cet article ?
0 0
110 Comments
  1. Thanks for sharing the article, and more importantly, your personal experience! Mindfully using our emotions as data about our inner state and knowing when it’s better to de-escalate by taking a time out are great tools. Appreciate you reading and sharing your story, since I can certainly relate and I think others can too.

    Free Download Vector Design For International Clients(United States of America)

    Répondre
  2. lipitor 80mg brand lipitor 80mg sale atorvastatin 80mg cheap

    Répondre
  3. propecia pills cost finasteride 5mg buy generic fluconazole

    Répondre
  4. propecia buy online buy diflucan 200mg without prescription fluconazole over the counter

    Répondre
  5. ciprofloxacin 500mg uk – buy generic cephalexin 500mg buy augmentin generic

    Répondre
  6. buy cipro 500mg online – clavulanate over the counter buy clavulanate no prescription

    Répondre
  7. purchase cipro – purchase augmentin sale augmentin 1000mg usa

    Répondre
  8. buy ciprofloxacin 500mg without prescription – trimethoprim oral oral augmentin 1000mg

    Répondre
  9. ciplox 500 mg pill – chloramphenicol brand erythromycin pills

    Répondre
  10. cheap flagyl 400mg – order terramycin without prescription zithromax usa

    Répondre
  11. baHeodySpFAQjqY

    Répondre
  12. buy ciprofloxacin 500 mg generic – order erythromycin 500mg pill buy cheap generic erythromycin

    Répondre
  13. buy generic metronidazole – cleocin 150mg generic purchase azithromycin generic

    Répondre
  14. dqAcyoZsmewGia

    Répondre
  15. ivermectin 3 mg pills – tetracycline 500mg brand buy tetracycline 500mg online

    Répondre
  16. ivermectin medication – oral suprax 200mg tetracycline 500mg cheap

    Répondre
  17. order generic valacyclovir 500mg – valacyclovir medication zovirax cheap

    Répondre
  18. UqyZcXNxnVvjt

    Répondre
  19. valtrex 1000mg uk – buy vermox without prescription order acyclovir 400mg sale

    Répondre
  20. where to buy acillin without a prescription monodox brand buy amoxicillin paypal

    Répondre
  21. order metronidazole 400mg for sale – cheap cefaclor 250mg purchase azithromycin pills

    Répondre
  22. buy acillin pills how to get amoxil without a prescription amoxicillin medication

    Répondre
  23. buy flagyl without prescription – buy cheap azithromycin where can i buy azithromycin

    Répondre
  24. buy lasix 100mg sale – captopril 25 mg brand capoten 25 mg generic

    Répondre
  25. brand furosemide – cost candesartan 8mg buy captopril 25 mg sale

    Répondre
  26. buy metformin 1000mg generic – order cipro 1000mg pill lincocin 500mg tablet

    Répondre
  27. brand glycomet 500mg – order metformin 1000mg pills order lincomycin online cheap

    Répondre
  28. how to buy retrovir – order epivir sale generic zyloprim

    Répondre
  29. clozapine 50mg generic – generic frumil 5mg pepcid 40mg generic

    Répondre
  30. clozapine drug – buy famotidine 20mg online order famotidine 20mg without prescription

    Répondre
  31. order generic quetiapine – venlafaxine 75mg canada purchase eskalith pill

    Répondre
  32. purchase quetiapine – order venlafaxine 150mg for sale buy eskalith pills for sale

    Répondre
  33. order clomipramine 50mg – clomipramine 25mg tablet doxepin 25mg us

    Répondre
  34. cost atarax 10mg – fluoxetine us endep order online

    Répondre
  35. generic hydroxyzine – buy prozac 20mg generic order endep generic

    Répondre
  36. buy augmentin 1000mg sale – baycip online cipro 1000mg generic

    Répondre
  37. purchase augmentin pills – buy ampicillin online ciprofloxacin 1000mg generic

    Répondre
  38. cheap amoxicillin – buy amoxicillin no prescription cipro 1000mg drug

    Répondre
  39. buy amoxicillin – order cefuroxime buy generic ciprofloxacin 1000mg

    Répondre
  40. buy azithromycin 250mg sale – azithromycin pills ciplox canada

    Répondre
  41. buy cleocin online – buy generic doxycycline online purchase chloromycetin sale

    Répondre
  42. order azithromycin 250mg pill – flagyl over the counter order ciplox 500 mg generic

    Répondre
  43. buy cleocin tablets – cefixime drug buy generic chloramphenicol

    Répondre
  44. ivermectin pills canada – buy cheap generic cefaclor order cefaclor pill

    Répondre
  45. ivermectin 3 mg tablets – stromectol usa order cefaclor 250mg pills

    Répondre
  46. albuterol sale – purchase albuterol inhaler order theo-24 Cr generic

    Répondre
  47. buy ventolin generic – seroflo buy online theophylline 400 mg tablet

    Répondre
  48. brand medrol – cetirizine medication astelin where to buy

    Répondre
  49. buy clarinex generic – buy albuterol 4mg online cheap buy albuterol 2mg pills

    Répondre
  50. methylprednisolone buy online – buy montelukast 10mg online brand astelin

    Répondre
  51. buy clarinex 5mg pills – clarinex 5mg without prescription purchase ventolin inhalator without prescription

    Répondre
  52. order glucophage pills – buy cozaar precose without prescription

    Répondre
  53. micronase usa – forxiga 10mg ca forxiga 10 mg ca

    Répondre
  54. OXGSDxnB

    Répondre
  55. order micronase 5mg sale – pioglitazone order online buy forxiga without prescription

    Répondre
  56. buy repaglinide 1mg for sale – buy generic repaglinide 1mg buy jardiance generic

    Répondre
  57. pdQEfPFGAXLIM

    Répondre
  58. buy glucophage 1000mg without prescription – januvia brand buy precose 50mg generic

    Répondre
  59. buy prandin generic – buy empagliflozin online jardiance usa

    Répondre
  60. order rybelsus 14 mg without prescription – semaglutide usa buy desmopressin for sale

    Répondre
  61. oral lamisil 250mg – buy lamisil no prescription griseofulvin online order

    Répondre
  62. order nizoral 200mg without prescription – cost sporanox 100mg purchase sporanox without prescription

    Répondre
  63. famvir 500mg ca – buy acyclovir for sale valaciclovir 500mg pill

    Répondre
  64. buy nizoral – itraconazole order online buy sporanox tablets

    Répondre
  65. order famciclovir 250mg pill – buy valcivir without prescription valaciclovir pill

    Répondre
  66. buy digoxin 250 mg online – order digoxin 250 mg generic order furosemide 40mg generic

    Répondre
  67. lanoxin online buy – cost verapamil buy lasix generic

    Répondre
  68. hydrochlorothiazide 25 mg tablet – purchase plendil online zebeta over the counter

    Répondre
  69. buy cheap generic metoprolol – order cozaar 50mg for sale nifedipine 30mg uk

    Répondre
  70. buy microzide 25mg without prescription – microzide 25 mg over the counter how to buy zebeta

    Répondre
  71. crestor online expensive – rosuvastatin pills hunter caduet pills corp

    Répondre
  72. buy viagra professional remind – viagra professional lett levitra oral jelly online relate

    Répondre
  73. cenforce online leg – tadalis pills contrary brand viagra online flash

    Répondre
  74. brand cialis defend – tadora terror penisole flicker

    Répondre
  75. acne treatment sleep – acne treatment permit acne medication cheap

    Répondre
  76. inhalers for asthma chance – asthma treatment foul asthma treatment ridge

    Répondre
  77. prostatitis pills wade – prostatitis pills treat pills for treat prostatitis those

    Répondre
  78. treatment for uti officer – treatment for uti comment treatment for uti indifferent

    Répondre
  79. valacyclovir thorough – valacyclovir pills grief valacyclovir online stable

    Répondre
  80. ascorbic acid bye – ascorbic acid odour ascorbic acid school

    Répondre
  81. promethazine purchase – promethazine haul promethazine expensive

    Répondre
  82. ascorbic acid talent – ascorbic acid gap ascorbic acid number

    Répondre
  83. promethazine agony – promethazine relieve promethazine fog

    Répondre
  84. biaxin peak – ranitidine pleasant cytotec pills pretty

    Répondre
  85. biaxin pills william – mesalamine delay cytotec pills empty

    Répondre
  86. florinef next – prevacid pills ireland prevacid pills tongue

    Répondre
  87. fludrocortisone pills wary – protonix pills fact prevacid whirl

    Répondre
  88. how to buy rabeprazole – metoclopramide 10mg without prescription oral domperidone

    Répondre
  89. buy rabeprazole online cheap – order metoclopramide 20mg without prescription order motilium 10mg generic

    Répondre
  90. dulcolax price – dulcolax 5 mg tablet purchase liv52 sale

    Répondre
  91. aciphex usa – metoclopramide drug buy cheap domperidone

    Répondre
  92. order dulcolax 5mg sale – order bisacodyl generic liv52 20mg pill

    Répondre
  93. hydroquinone canada – duphaston 10 mg sale buy duphaston 10mg online

    Répondre
  94. purchase forxiga pills – order acarbose 50mg online acarbose where to buy

    Répondre
  95. purchase enalapril sale – buy vasotec pills buy cheap generic xalatan

    Répondre
  96. enalapril 5mg tablet – order doxazosin 2mg sale buy xalatan generic

    Répondre
  97. etodolac generic – order etodolac 600 mg generic pletal cost

    Répondre
  98. buy etodolac 600mg generic – order pletal 100mg for sale pletal uk

    Répondre
  99. order piroxicam 20 mg sale – buy rivastigmine 3mg online cheap generic rivastigmine

    Répondre
  100. piroxicam 20 mg ca – brand piroxicam 20mg order generic exelon

    Répondre
  101. buy piracetam 800mg – biltricide over the counter buy sinemet 20mg

    Répondre

Laisser une réponse

Votre adresse e-mail ne sera pas publiée. Les champs requis sont marqués *

You may use these HTML tags and attributes: <a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>