Situation épidémique en République Démocratique du Congo (RDC) – Virus Ebola (EBOV)
Epidémie en cours depuis le 1er août 2018 dans la province du North Kivu, RDC.
Situation au 10/06/2019 : au total 2062 cas (1968 confirmés et 94 probables), 1390 décès (67%de mortalité) et plus 560 individus guéris.
Informations et suivi en temps réel sur le compte Twitter du Compte officiel du Ministère de la Santé de la République Démocratique du Congo : https://twitter.com/MinSanteRDC
Points clés sur le virus Ebola (EBOV) …
- Virus de la famille des Filoviridae
- La maladie à virus Ebola (autrefois appelée aussi fièvre hémorragique à virus Ebola) est une maladie grave, souvent mortelle chez l’humain.
- Le taux de létalité moyen est d’environ 50%, ce taux peut atteindre les 90%.
- Le virus se transmet à l’humain à partir des animaux sauvages (zoonose) et se propage ensuite dans les populations par transmission interhumaine.
- Les soins de soutien précoces axés sur la réhydratation et le traitement symptomatique améliorent les taux de survie. Aucun traitement homologué à ce jour, mais plusieurs pistes sont à l’étude (vaccins, anticorps monoclonal [ZMapp] et antiviraux en développement expérimental [inhibiteur de polymérase virale, favipiravir et remdesivir])
- La prévention des cas humains repose sur plusieurs facteurs :
- Réduction du risque de transmission entre les animaux sauvages et l’humain Réduction du risque de transmission interhumaine via les liquides biologiques infectés
- Inhumation rapide et sans risque des individus décédés, identification des cas contact avec une personne infectée par EBOV, séparation des individus sains/malades pour prévenir la propagation du virus
- Réduction du risque potentiel de transmission sexuelle (recommandation : aucun rapport sexuel pendant 12 mois chez les survivants)
Pour en savoir plus …
https://viralzone.expasy.org/207?outline=all_by_species
https://www.cdc.gov/vhf/ebola/index.html
https://www.who.int/ebola/en/
Revue récente dans le journal Lancet : Malvy D, McElroy AK, de Clerck H, Günther S, van Griensven J. Ebola virus disease. Lancet. 2019 Mar 2;393(10174):936-948. https://www.ncbi.nlm.nih.gov/pubmed/30777297
CNR Fièvres hémorragiques virales :
https://www.pasteur.fr/fr/sante-publique/CNR/les-cnr/fievres-hemorragiques-virales
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