Title:
“Physiology of new hydrothermal microorganisms able to disproportionate inorganic sulfur compounds”
« Physiologie de nouveaux microorganismes hydrothermaux capables de réaliser la dismutation du soufre »
Scientific context:
Sulfur disproportionation is a metabolism rather original, rather poorly characterized and which has been recently discovered at high temperature. Microorganisms able to disproportionate inorganic sulfur compounds can use a same molecule as electron donor and acceptor (elemental sulfur, sulfite, thiosulfate) to produce energy. Sulfur disproportionating microorganisms known so far are all bacteria and are present in a wide diversity of environments (Ollivier et al. 2018). Moreover, sulfur disproportionation could be one of the first primitive microbial metabolism on earth according to some hypotheses (Philippot et al. 2007). Hydrothermal ecosystems are particularly rich in sulfur compounds or diverse redox states and could also be related to origin of life, and then make a perfect environment to search for new sulfur disproportionating microorganisms and describe their metabolic routes.
Internship aim:
The main goal of this Master 2 internship will be to discover and to characterize one or two new microorganisms able to disproportionate inorganic sulfur compounds, in order to expand our knowledge about these microorganisms and their energy-producing pathways. To do this, we have a collection of deep marine hydrothermal samples collected from all around the world, from which enrichment cultures are already in progress. As soon as a strain has been isolated, the aim will be to characterize its physiology and analyze its genomic potential, in order to describe the underlying metabolic pathways. Growth range and optimum will be determined for several physical chemical conditions (e.g. temperature, pH, salinity) by growth monitoring. Cell morphology will be determined by TEM and SEM. The sulfur species range and metabolic intermediates will be analyzed by combining analytical approaches (GC, IC) and colorimetric reactions. The phylogenetic position of the novel isolate will be analyzed by 16S rRNA gene sequence and full genome sequencing. The genome will also be annotated to describe the pathway of sulfur disproportionation. If motivated, the intern will also have the chance to test already known and characterized hydrothermal microbial species for their capability to grow via sulfur disproportionation. Culturing will be time and effort consuming and will require a good organization and time managing.
Candidate profile:
Motivated student in microbiology, metabolism and physiology areas.
Experience with anaerobic microbial cultures will be a bonus but not a requirement.
Curiosity and interest for wet lab culture experiments.
Contact:
This project is part of the NEPTUNE project, based on a French-Russian collaboration, which is focused on poorly documented metabolisms related to nitrogen and sulfur cycles in hydrothermal vents. It is also part of the Sino-French associated international laboratory MicrobSea. Internship will be made at the LM2E laboratory, at the IUEM institute, located in Plouzané (29) (https://wwz.ifremer.fr/umr6197/), under the supervision of Dr. Karine ALAIN and the 2nd year PhD student Maxime ALLIOUX.
Please send a motivation letter, a CV and transcripts from the last 3 years to
Maxime ALLIOUX :Maxime.Allioux@univ-brest.fr
And Karine ALAIN : Karine.Alain@univ-brest.fr
If you have any questions, please do not hesitate to contact us
References:
Finster, K. (2008). Microbiological disproportionation of inorganic sulfur compounds. J. Sulfur Chem. 29, 281–292. doi: 10.1080/17415990802105770
Ollivier, B., Zeyen, N., Gales, G., Hickman-Lewis, K., Gaboyer, F., Benzerara, K., & Westall, F. (2018). Importance of Prokaryotes in the Functioning and Evolution of the Present and Past Geosphere and Biosphere BT – Prokaryotes and Evolution (J.-C. Bertrand, P. Normand, B. Ollivier, & T. Sime-Ngando, eds.). https://doi.org/10.1007/978-3-319-99784-1_3
Philippot, P., Zuilen, M. Van, Lepot, K., Thomazo, C., Farquhar, J., & Kranendonk, M. J. Van. (2007). Early Archaean Microorganisms Preferred Elemental Sulfur, Not Sulfate, 317(September), 1534–1538. doi: 10.1126/science.1145861
Lpjyfy
purchase lipitor sale cost lipitor 40mg buy atorvastatin cheap
Tqklhy
proscar 5mg without prescription finasteride pills purchase forcan without prescription
Nhfagd
ciprofloxacin us – cipro brand buy augmentin 375mg pills
Fyvjnr
buy cipro 1000mg online cheap – cheap bactrim 480mg augmentin cost
Ixszxy
order flagyl 200mg pills – buy azithromycin 250mg online cheap zithromax 250mg drug
Pplqiq
ciprofloxacin 500mg sale – ciplox 500 mg ca buy erythromycin 250mg generic
Tvooqc
stromectol otc – ciplox cost tetracycline 500mg for sale
Hkfbhl
order valacyclovir 1000mg for sale – buy valtrex 500mg for sale acyclovir 800mg drug
Ukfpft
ampicillin canada buy acillin generic amoxil over the counter
Copwnk
buy glucophage 1000mg without prescription – bactrim 480mg uk buy lincomycin 500 mg for sale
Jajrvd
buy generic clozapine 100mg – frumil without prescription buy famotidine cheap
Fotllt
buy quetiapine 50mg online – cheap eskalith pill purchase eskalith generic
Ajlbqt
clomipramine cost – order asendin 50mg without prescription buy sinequan 25mg online
Qcbcdw
amoxiclav oral – linezolid 600mg price order ciprofloxacin 1000mg sale
Zhhves
order generic amoxil – buy erythromycin sale buy ciprofloxacin 500mg generic
Kbmsqw
buy azithromycin 250mg without prescription – sumycin 500mg brand buy ciplox pills
Acfmse
buy cleocin generic – purchase doxycycline pills buy chloromycetin cheap
Szczegóły tutaj
Outstanding feature
Yjyjvo
ivermectin 12mg tablet – aczone over the counter cefaclor pills
Lcswtn
albuterol inhalator buy online – order theophylline 400 mg pills order theo-24 Cr 400mg generic
Jqpmnn
desloratadine cost – where can i buy triamcinolone order albuterol 2mg sale
Uxmcgy
order micronase 5mg online – buy actos 15mg generic buy generic forxiga over the counter
Tyblwp
glucophage 1000mg tablet – metformin 1000mg without prescription buy precose 50mg for sale
Ycyvbb
repaglinide for sale – buy cheap jardiance cost jardiance 25mg
Mthicb
order terbinafine online cheap – order generic lamisil purchase grifulvin v generic
Zfntzb
rybelsus 14mg canada – buy rybelsus online cheap order DDAVP online
Lrounn
famvir 500mg brand – acyclovir 400mg sale valaciclovir where to buy
Ocebon
order lanoxin 250 mg generic – calan cost order lasix 100mg pills
Jggxfj
nitroglycerin usa – order generic nitroglycerin valsartan pill
Rzziox
inhalers for asthma kitty – inhalers for asthma type asthma treatment roger
Xboghy
ascorbic acid wheel – ascorbic acid fro ascorbic acid soar
Piikmr
promethazine detail – promethazine credit promethazine along
Xjcvvq
clarithromycin pills fill – mesalamine pills sir cytotec pills astonish
Kelwcp
fludrocortisone pills sock – protonix lone prevacid impress
Soipyf
aciphex 10mg price – order generic metoclopramide purchase domperidone pills
Ktwxsa
buy bisacodyl generic – buy generic bisacodyl cost liv52 20mg
Gkkakx
order zovirax generic – buy generic eukroma duphaston 10mg price
Ormpae
forxiga buy online – order forxiga online order acarbose 50mg generic
Gdfrnk
monograph 600mg ca – order etodolac 600 mg for sale buy cilostazol no prescription
Mldvjb
feldene usa – piroxicam cheap buy rivastigmine cheap
Hihsrv
piracetam 800mg over the counter – purchase sustiva online cheap purchase sinemet pills
Larrynub
pin up yukle: pin-up kazino – pin-up 141
Rtmcoe
hydrea brand – hydroxyurea price buy generic robaxin
Jeffreymycle
https://northern-doctors.org/# mexican mail order pharmacies
RichardJeave
buying prescription drugs in mexico online mexican northern doctors mexican border pharmacies shipping to usa
Jeffreymycle
https://northern-doctors.org/# mexican pharmacy
Jeffreymycle
https://northern-doctors.org/# buying prescription drugs in mexico online
Williamadvam
mexican drugstore online: Mexico pharmacy that ship to usa – mexico drug stores pharmacies
RichardJeave
mexico pharmacies prescription drugs mexican pharmacy online mexican drugstore online
Jeffreymycle
http://northern-doctors.org/# mexican online pharmacies prescription drugs
Williamadvam
buying from online mexican pharmacy: mexican pharmacy northern doctors – mexican pharmaceuticals online
Jeffreymycle
https://northern-doctors.org/# mexican border pharmacies shipping to usa
Jeffreymycle
https://northern-doctors.org/# pharmacies in mexico that ship to usa
RichardJeave
mexican rx online mexican pharmacy medication from mexico pharmacy
Jeffreymycle
https://northern-doctors.org/# mexico drug stores pharmacies
Williamadvam
mexico drug stores pharmacies: mexican northern doctors – mexico drug stores pharmacies
Jeffreymycle
http://northern-doctors.org/# п»їbest mexican online pharmacies
RichardJeave
mexico drug stores pharmacies п»їbest mexican online pharmacies mexico drug stores pharmacies
Jeffreymycle
https://northern-doctors.org/# mexican mail order pharmacies
RichardJeave
buying from online mexican pharmacy medicine in mexico pharmacies pharmacies in mexico that ship to usa
Jeffreymycle
https://northern-doctors.org/# mexico pharmacies prescription drugs
Jeffreymycle
https://northern-doctors.org/# medication from mexico pharmacy
Jeffreymycle
http://northern-doctors.org/# mexican border pharmacies shipping to usa
RichardJeave
purple pharmacy mexico price list mexican pharmacy online best online pharmacies in mexico
Jeffreymycle
https://northern-doctors.org/# mexican mail order pharmacies
Jeffreymycle
http://northern-doctors.org/# mexico drug stores pharmacies
RichardJeave
medication from mexico pharmacy northern doctors pharmacy mexico pharmacies prescription drugs
Jeffreymycle
https://northern-doctors.org/# buying from online mexican pharmacy
Jeffreymycle
https://northern-doctors.org/# best online pharmacies in mexico
Jeffreymycle
https://northern-doctors.org/# mexican online pharmacies prescription drugs
RichardJeave
mexico drug stores pharmacies mexican pharmacy mexico pharmacies prescription drugs
Jeffreymycle
https://northern-doctors.org/# mexico pharmacies prescription drugs
Ronniesig
mexican rx online mexican pharmacy online best online pharmacies in mexico
Djqloy
divalproex price – amiodarone 200mg us topiramate 100mg pills
Ronniesig
buying from online mexican pharmacy cmqpharma.com reputable mexican pharmacies online
Ronniesig
mexican pharmacy mexican pharmacy online mexico pharmacies prescription drugs
Ronniesig
best online pharmacies in mexico mexican online pharmacy mexican border pharmacies shipping to usa
Ronniesig
п»їbest mexican online pharmacies mexico pharmacies prescription drugs mexico drug stores pharmacies
Ronniesig
п»їbest mexican online pharmacies mexico pharmacies prescription drugs purple pharmacy mexico price list
Ronniesig
pharmacies in mexico that ship to usa reputable mexican pharmacies online purple pharmacy mexico price list
Ngewvo
order disopyramide phosphate online – order lamotrigine pill buy thorazine without prescription
Ronniesig
best online pharmacies in mexico online mexican pharmacy pharmacies in mexico that ship to usa
Jeffreyrig
http://cmqpharma.com/# mexican rx online
mexico drug stores pharmacies
Rmhdmi
purchase spironolactone generic – dipyridamole without prescription buy generic revia online
Yhbvqx
cytoxan buy online – stavudine uk buy generic trimetazidine for sale
Wnzvqz
flexeril where to buy – vasotec 5mg brand vasotec 10mg ca
Hjrdub
buy ascorbic acid 500mg pill – purchase ascorbic acid generic order prochlorperazine pills
Amwnns
durex gel order online – order durex gel cheap buy cheap generic zovirax
Henryskarm
mexican border pharmacies shipping to usa: cmq mexican pharmacy online – mexican pharmaceuticals online
Zqgzxg
order rogaine online – rogaine canada order finasteride 5mg generic
Qzhstn
order generic leflunomide – risedronate pills cheap cartidin without prescription
Tuicgg
calan tablet – purchase tenoretic online cheap purchase tenoretic pill
Mjotfs
order atorlip online cheap – purchase vasotec online nebivolol 5mg sale
Wkeokb
cheap gasex pills – buy gasex diabecon pills
Edwardmop
http://foruspharma.com/# mexican rx online
Michaelhig
india pharmacy mail order: cheapest online pharmacy india – Online medicine home delivery
Michaelhig
canadian world pharmacy: pharmacy canadian – real canadian pharmacy
Davidoceat
indian pharmacies safe: mail order pharmacy india – buy prescription drugs from india
Edwardmop
http://canadapharmast.com/# thecanadianpharmacy
Davidoceat
top 10 pharmacies in india: cheapest online pharmacy india – indian pharmacies safe
Charleskep
п»їbest mexican online pharmacies mexican mail order pharmacies buying from online mexican pharmacy
Davidoceat
mexican mail order pharmacies: best online pharmacies in mexico – mexico pharmacy
Michaelhig
top online pharmacy india: buy prescription drugs from india – indian pharmacy
Michaelhig
canadian online pharmacy reviews: reliable canadian pharmacy reviews – pharmacy wholesalers canada
Davidoceat
top 10 online pharmacy in india: buy medicines online in india – online shopping pharmacy india
Edwardmop
http://canadapharmast.com/# legal canadian pharmacy online
Davidoceat
safe online pharmacies in canada: canada drug pharmacy – canadian pharmacy 24 com
Davidoceat
п»їlegitimate online pharmacies india: indian pharmacy paypal – world pharmacy india
Michaelhig
canadian drugs pharmacy: canadian pharmacies comparison – reputable canadian pharmacy
Mxssja
lasuna tablets – lasuna price cheap himcolin online
Edwardmop
https://foruspharma.com/# mexican rx online
Davidoceat
best canadian pharmacy online: best online canadian pharmacy – best canadian pharmacy online
Charleskep
purple pharmacy mexico price list mexican pharmacy mexico pharmacies prescription drugs
Edwardmop
http://canadapharmast.com/# pharmacy canadian superstore
Davidoceat
india pharmacy: online shopping pharmacy india – india pharmacy mail order
Michaelhig
cheap canadian pharmacy: canadian pharmacy 1 internet online drugstore – northwest canadian pharmacy
Michaelhig
online pharmacy india: cheapest online pharmacy india – п»їlegitimate online pharmacies india
Davidoceat
mexican pharmacy: mexico drug stores pharmacies – buying prescription drugs in mexico online
Jameslab
doxycycline pharmacy online: doxycycline 200 mg price in india – buy doxycycline online
ThomasErert
http://ciprodelivery.pro/# cipro for sale
Jameslab
buying clomid tablets: get clomid – can i purchase generic clomid pills
ThomasErert
https://doxycyclinedelivery.pro/# cost of doxycycline prescription 100mg
ThomasErert
https://paxloviddelivery.pro/# paxlovid buy
Jameslab
where to buy amoxicillin 500mg without prescription: amoxicillin price canada – amoxicillin online canada
Jameslab
buy cipro online canada: buy cipro online usa – cipro ciprofloxacin
ThomasErert
https://clomiddelivery.pro/# clomid price
Jameslab
buy ciprofloxacin over the counter: buy generic ciprofloxacin – ciprofloxacin order online
ThomasErert
http://paxloviddelivery.pro/# п»їpaxlovid
Jameslab
amoxicillin 200 mg tablet: amoxil generic – where to get amoxicillin over the counter
ThomasErert
https://ciprodelivery.pro/# cipro for sale
ThomasErert
https://clomiddelivery.pro/# where can i buy clomid without rx
Jameslab
2985 doxycycline: buy generic doxycycline – doxycycline capsules
Jameslab
can i order cheap clomid tablets: how can i get clomid no prescription – cost clomid without a prescription
ThomasErert
https://ciprodelivery.pro/# cipro 500mg best prices
Jameslab
where can i get cheap clomid: order generic clomid pills – clomid medication
ThomasErert
https://ciprodelivery.pro/# buy cipro cheap
Jameslab
buy cipro no rx: cipro pharmacy – buy generic ciprofloxacin
ThomasErert
https://amoxildelivery.pro/# where can i buy amoxocillin
ThomasErert
https://doxycyclinedelivery.pro/# where can i buy doxycycline without prescription
Jameslab
buy paxlovid online: paxlovid for sale – paxlovid buy
ThomasErert
https://amoxildelivery.pro/# buy amoxicillin 500mg capsules uk
Jameslab
doxycycline rx: doxycycline 75 mg cost – doxycycline tetracycline
Jameslab
paxlovid pill: Paxlovid buy online – paxlovid price
Jameslab
amoxicillin 500 mg: amoxicillin buy canada – amoxicillin 500mg buy online canada
Jameslab
amoxicillin order online: amoxicillin online no prescription – buy amoxicillin online cheap
Vdgqmc
order speman generic – buy generic speman purchase finasteride