Et si le secret pour lutter contre certains pathogènes bactériens résistants aux antibiotiques se trouvait juste sous nos pieds, dans des environnements aqueux, telluriques ou simplement du compost ?
C’est à cette question peu banale que le laboratoire du Dr. Xavier Charpentier, basé au Centre International de Recherche en Infectiologie (Lyon, France), s’est intéressé dans leur étude parue dans la revue Applied and Environmental Microbiology.
Dans cet article Félix Bornier, doctorant, et ses collaborateurs ont pu démontrer que certaines amibes environnementales, isolées à partir de compost, possèdent la capacité naturelle d’éradiquer de nombreux pathogènes tels que Acinetobacter baumannii, Klebsiella pneumoniae, Pseudomonas aeruginosa ou encore Staphylococcus aureus.
De manière fascinante, certaines de ces amibes appartenant aux genres Vermamoeba, Tetramitus, Acanthamoeba, Vahlkampfia ou Stemonitis, étaient non seulement capables de se nourrir de souches conventionnelles de laboratoire, mais également d’isolats cliniques hautement virulents résistants aux carbapénèmes ou à la méticilline.
Notre avis ? A lire absolument ici : https://journals.asm.org/doi/10.1128/AEM.00747-21
Bornier, F., Zas, E., Potheret, D., Laaberki, M. H., Coupat-Goutaland, B., & Charpentier, X. (2021). Environmental Free-Living Amoebae Can Predate on Diverse Antibiotic-Resistant Human Pathogens. Applied and environmental microbiology, 87(18), e0074721. https://doi.org/10.1128/AEM.00747-21
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