Two post-doctoral positions available on antifungal drug resistance, Institut Pasteur Paris

In the framework of a French–German collaborative project on antifungal drug resistance, we are looking for two highly motivated post-doctoral fellows.

The two fellows will perform a comprehensive analysis of the contribution of protein kinases to antifungal resistance in the fungal pathogens Candida glabrata, Candida auris and Aspergillus fumigatus. Protein kinases holds a key position in the regulation of multiple metabolic processes but less than 30% have been functionally characterized in these species. The projects will combine molecular approaches to the function of protein kinases in antifungal resistance and tolerance as well as the identification and characterization of kinase inhibitors with relevant activities in the investigated species.

The first position is available in the Fungal Biology and Pathogenicity Unit under the supervision of Prof. Christophe d’Enfert and will focus on protein kinases of the yeasts Candida glabrata and Candida auris. The second position is available in the RNA Biology and Fungal pathogens Unit under the supervision of Dr. Isabelle Mouyna and will focus on protein kinases of the filamentous fungus Aspergillus fumigatus.

Applicants should possess demonstrated experience in molecular biology, functional genomics, biochemistry, microbiology and mycology. The successful applicants will have a high degree of flexibility in research directions and approaches. The positions are available from April 1st, 2020 for a period of 2 years.

Applications consisting of a CV, publication list and a detailed statement of research interests, with names and contact information for 2 references should be prepared as a single pdf file and sent by email to christophe.denfert@pasteur.fr (for the Candida species position) and imouyna@pasteur.fr (for the Aspergillus fumigatus position) before March 15th, 2020. Applications will be processed as they are received.

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